Cytologic Study on Prevention and Treatment of Primary Osteoporosis with Chinese Drugs for Tonifying the Kidney[J]. Journal of Traditional Chinese Medicine2001, (10): 621-623.
Cytologic Study on Prevention and Treatment of Primary Osteoporosis with Chinese Drugs for Tonifying the Kidney[J]. Journal of Traditional Chinese Medicine2001, (10): 621-623.DOI: 10.13288/j.11-2166/r.2001.10.028.
In order to compare differences of effects of complex prescription for reinforcing the kidney on osteoblast (OB) and osteoclast (OC)
MTT method was used to determine proliferous capability of OB
bone lacuna count was used for quantitative assessment of absorbent activity of OC. Results showed that the mean influencing rate of Jin Gui Shen Qi Pill
Bu Shen Yi Jing Prescription
Zhi Bai Di Huang Pill
and Western medicine Premarin tablet for proliferous capability of OB was 159. 2%
121. 5%
21. 6% and 75. 7% respectively; the mean influencing rate for bone lacuna count was 50. 2%
21. 0%
19. 8% and 38. 1% respectively
suggesting that the drug for even reinforcing Yin and Yang can improve proliferation of OB and inhibit activity of OC
and increase of the drug for warming Yang can strengthen the promoting action on proliferation of OB
but increase of the drug for nourishing Yin had opposed action
the drugs for nourishing Yin plus the drugs for purging the pathologic fire can inhibit activity of OC and proliferation of OB.