Under the guidance of the Liu’s theory of kidney deficiency and incubative pathogen

the authors point out that for understanding the incubative pathogen of chronic hepatitis B （CHB） you should grasp the essence of the pathogenesis

kidney deficiency. For chronic hepatitis B

it is easier to be understood and conforms to pathological characteristics of chronic hepatitis B. The property of the incubative pathogen can not be restricted to that the incubative cold changes to warm

it should be understood as epidemic heat and epidemic toxin. Therefore

the authors first put forward this hypothesis: the pathogenesis of chronic hepatitis B is kidney deficiency and damp-heat toxic pathogen incubating in liver and blood. And based on the hypothesis a comprehensive therapy including clearing away heat

expelling pathogenic factors

promoting blood circulation and tonifying the kidney is introduced.