Zhang Hongxia, Liu Jiangang, Shi Dazhuo. Effects of Qixue Bingzhi Prescription on Hypersensitive C-reactive Protein and Other Indexes in the Patient of Cervical Atherosclerosis[J]. Journal of Traditional Chinese Medicine2004, (12): 907-910.
Zhang Hongxia, Liu Jiangang, Shi Dazhuo. Effects of Qixue Bingzhi Prescription on Hypersensitive C-reactive Protein and Other Indexes in the Patient of Cervical Atherosclerosis[J]. Journal of Traditional Chinese Medicine2004, (12): 907-910.DOI: 10.13288/j.11-2166/r.2004.12.015.
Objective:To study intervenient action of Qixue Bingzhi Prescription on the patient of cervical atherosclerosis(AS). Methods:63 cases of cervical AS were randomly divided into a treatment group(n=33) and a control group(n=30)
with 25 cases of same age ranges used as healthy group. The control group was treated with basic treatment of western medicine and the treatment group with the basic treatment plus Qixue Bingzhi Prescription for one month. Changes of blood lipid metabolism
interleukin levels
supersensitive C-reactive protein(Hs-CRP) content and the leukocyte adherence expression rate were observed. Results: The total cholesterol (TC)
triglyceride(TG)
AS index (TC/HDL-C)
interleukin-6 (IL-6)
interleukin-8 (IL-8) and Hs-CRP levels and lymphocytes and the neutrophilic granulocyte adhesion molecule expression rate (ICD11b and zCD11b) decreased significantly(P <0. 05) in the treatment group
with significant decrease of TC/HDL-C and more significant effects on IL-6
Hs-CRP and ICD11b as compared with the control group after treatment. The indexes of safety before and after treatment did not have significant changes (P>0. 05)
Conclusion: Qixue Bingzhi Prescription can effectively and safely intervene in blood lipid metabolism and inflammatory reaction in the patient of cervical AS
and it has prospect of development in preventing formation of AS and stabilizing plaque.