Objective:To study on effects of Chinese herbs for removing toxic substances

nourishing Yin and removing blood stasis on activity of disease in the patient of systemic lupus erythematosus（SLE）.Methods:65 cases of SLE were divided into a Chinese medicine group and a control group

and their cumulative scores of SLE disease activity index and changes of doses of prednisone were observed before and after treatment of 2 courses

respectively.Results:At the end of the second treatment course

there was significant difference in the number of case at the active stage and the resting stage between the two groups（P<0.05）

and the daily withdrawing amount of prednisone was superior to that in the control group（P<0.01）.Conclusion:The Chinese herbs for removing toxic substances

nourishing Yin and removing blood stasis can control activity of disease and also can reduce dose of prednisone for the patient of systemic lupus erythematosus.