Effects of Modified Yupingfeng Powder on Cellular Immune Function in Mice of Wound Stress[J]. Journal of Traditional Chinese Medicine2005, (5): 380-382.
Effects of Modified Yupingfeng Powder on Cellular Immune Function in Mice of Wound Stress[J]. Journal of Traditional Chinese Medicine2005, (5): 380-382.DOI: 10.13288/j.11-2166/r.2005.05.029.
Objective:To observe effects of modified Yupingfeng Powder on cellular immune function in mice of wound stress.Methods: Changes of cellular immune function were detected in mice of amputation stress.Results:In the mice after wound
cellular immune function including γ-interferon(IFN-γ)
CD
4
level
CD
4
/CD
8
ratio decreased
transforming growth factor-β(TGF-β)level and nuclear transcript factor(NF-kB)mRNA and interleukin-10(IL-10)mRNA expression increased;Modified Yupingfeng Powder of high
middle and low dosages could correct the above indexes in varying degrees
and the various indexes in the mice of the high dosage group all restored to normal.Conclusion:After wound
cellular immune function of the mice was inhibited
and modified Yupingfeng Powder can effectively restore cellular immune function.