Objective:To observe the therapeutic effect of modified Banxia Houpu Decoction on protracted abstinent syndrome after detoxification in heroin dependence.Methods:198 cases of heroin dependence were randomly divided into three groups

control group（n=63）

treatment group A（n=65）and B（n=70）.They were detoxified by using Lofexidine Hydrochloride Tablet（LFX） for 12 days

and then

the control group were treated with an imitative preparation

the treatment group A with modified Banxia Houpu Decoction for 60 days

and the treatment group B with the modified Baixia Houpu Decoction from the beginning of the detoxification with LFX.10 days after treatment of Chinese medicine was ceased

the protracted abstinent syndromes of the three groups were observed and scored for 7 days

and one year later

the drug re-abusing cases in the three groups were investigated through detection of heroin in urine.Results:The scores of the protracted abstinent syndromes in treatment group B were lower than in treatment group A（P<0.01）

and the scores in treatment group A were lower than in the control group（P<0.01）.The re-abusing rate in treatment group B were significantly lower than in the control group（P<0.05）.Conclusion:Modified Banxia Houpu Decoction can improve the protracted abstinent syndromes after detoxification from heroin

and possibly has the tendency to decrease the re abusing rate when it is early administrated.