Objective:To observe effects of Sanbaoxin on formation of thrombosis in vivo and in vitro in rats.Methods:After the rats were administrated by high

mid and low doses

i

e

10g crude drug/kg

5g/kg and 1g/kg

respectively

Chandler method was used to form in vitro thrombosis and electrical stimulation of common carotid artery was used to form in vivo thrombosis

and then effects of Sanbaoxin on formation of thrombosis were observed.Results:The high dosage of Sanbaoxin could significantly prolongate the period of in vivo thrombosis（P<0.05）;the high

mid and low doses all could significantly inhibit in vitro thrombosis

significantly shortening the length of thrombus（P<0.01）

reducing wet weight and dry weight of thrombus（P<0.05）.Conclusion: Sanbaoxin has inhibiting action on thrombosis.