Objective:To provide prospect and ideas for modern apply of TCM medicinal guide theory so as to better develop essence of TCM theories by means of studies on relation between TCM medicinal guide theory and modern target-tropism administration thought. Methods:Investigate

research

summarize and compare TCM medicinal guide theory

TCM channel tropism thought

and achievements of studies on TCM pharmacokinetics

physiology and biological preparation

and put forward argument and methods to test and verify.Results:TCM medicinal guide theory and modern target-tropism administration thought have similar points. Present achievements of studies on physiological and molecular biological techniques can provide methods for revealing their internal relations.Conclusion:The medicinal guide theory may apply to design the target-tropism administration system and overcome shortcomings of present target preparations.Studies on relation of the medicinal guide theory with target-tropism administration can help develop TCM theories and promote the studies on mechanisms of the channel-tropism drugs.