Yang Minghui Lu Junzhang Dou Yongqi. Clinical Observation on 30 Cases of Senile Type 2 Diabetes with Qi-Deficiency and Blood Stasis Treated with Baoyuan Huoxue Granule[J]. Journal of Traditional Chinese Medicine2005, (10): 750-752.
Yang Minghui Lu Junzhang Dou Yongqi. Clinical Observation on 30 Cases of Senile Type 2 Diabetes with Qi-Deficiency and Blood Stasis Treated with Baoyuan Huoxue Granule[J]. Journal of Traditional Chinese Medicine2005, (10): 750-752.DOI: 10.13288/j.11-2166/r.2005.10.013.
Objective:To explore effects of Baoyuan Huoxue Granule on senile type 2 diabetes with Qi deficiency and blood stasis
and expression rates of membrane glucoprotein selectin P(CD62p)and fibrin receptor(PAC-1)in the granule of platelet.Methods:60 cases of senile type 2 diabetes with Qi-deficiency and blood stasis were randomly divided into two groups
a simple western medicine control group(n=30)and a test group(n=30)treated by routine western medicine and Baoyuan Huoxue Granule.The treatment was given 2 months.Their clinical therapeutic effects
and the expression rates of CD62p and PAC-1 before and after treatment were investigated.Results:In the test group
12 cases(40%)were markedly effective
15 cases(50%)effective
3 cases (10%)ineffective
with an effective rate of 90%;In the control group
3 cases(10%)were markedly effective
12(40%) effective
15(50%)ineffective.the effective rate being 50%
with significant difference between the two groups in total effective rate(P<0.01).The expression rates of CD62p and PAC-1 in the test group after treatment decreased significantly(P<0.01). Conclusion:Baoyuan Huoxue Granule can improve syndromes of Qi-deficiency and blood stasis
and reduce the expression rates of CD62p and PAC-1 in the diabetic patient.