扶正解毒颗粒抗镍暴露肝损伤31例临床研究

吕晓云; 赵健雄; 滕玉莲

doi:10.13288/j.11-2166/r.2005.12.023

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扶正解毒颗粒抗镍暴露肝损伤31例临床研究

更新时间：2021-11-20

- 扶正解毒颗粒抗镍暴露肝损伤31例临床研究
- Clinical Study on Treatment with Fuzheng Jiedu Granule in 31 Cases of Hepatic Injury Induced by Nickel Exposure
- 中医杂志 2005年第12期页码：910-912
- 作者机构：
  
  1. 兰州大学中西医结合研究所
  2. 兰州大学校医院甘肃省兰州市东岗西路199号,730000
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2005.12.023
  中图分类号： R259
- 纸质出版：2005
- 稿件说明：
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[1]吕晓云,赵健雄,滕玉莲.扶正解毒颗粒抗镍暴露肝损伤31例临床研究[J].中医杂志,2005(12):910-912.

Clinical Study on Treatment with Fuzheng Jiedu Granule in 31 Cases of Hepatic Injury Induced by Nickel Exposure[J]. Journal of Traditional Chinese Medicine2005, (12): 910-912.
[1]吕晓云,赵健雄,滕玉莲.扶正解毒颗粒抗镍暴露肝损伤31例临床研究[J].中医杂志,2005(12):910-912. DOI： 10.13288/j.11-2166/r.2005.12.023.

Clinical Study on Treatment with Fuzheng Jiedu Granule in 31 Cases of Hepatic Injury Induced by Nickel Exposure[J]. Journal of Traditional Chinese Medicine2005, (12): 910-912. DOI： 10.13288/j.11-2166/r.2005.12.023.

摘要

目的:研究扶正解毒颗粒抗镍暴露肝损伤的临床疗效及其对血镍、肝功能、血象、心电图、B 超、X 线的影响。方法:将60例患者随机分为两组

治疗组31例采用扶正解毒颗粒合用门冬氨酸钾镁、促肝细胞生长素治疗;对照组29例仅用门冬氨酸钾镁、促肝细胞生长素治疗

疗程均为4周。观察血清镍、肝功能及血象、心电图等变化。结果:治疗组临床疗效、降镍作用、肝功能、异常血象、X 线、B 超及心电图的改善均优于对照组（P<0.05或 P<0.01）。结论:扶正解毒颗粒具有显著抗镍暴露肝损伤的作用。

Abstract

Objective:To observe the clinical therapeutic effect of Fuzheng Jiedu Granule（FJG）on hepatic injury induced by nickel exposure

and effects on serum nickel content

liver functions

blood cell

electrocardiogram

and findings of B-ultrasonography and X-ray. Methods:60 cases were randomly divided into two groups

treatment group（n=31）and control group（n=29）.The treatment group were treated with FJG combined with potassium-magnesium aspartate and hepatocyte growth-promoting factor

and the control group only with potassium-magnesium aspartate and hepatocyte growth-promoting factor.All of them were treated for 4 weeks.Changes of above indexes were investigated.Results:The treatment group was superior to the control group in the therapeutic effect on symptoms and signs

and in the improvement of the above indexes（P<0.05 or P<0.01）.Conclusion:FJG plays a significant role in antagonizing hepatic injury induced by nickel exposure.

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