Objective:To evaluate and compare the therapeutic effects of Chinese medicine and intra-arterial chemotherapy for stage Ⅳ pancreatic cancer patients.Methods:From May 2002 to July 2004

60 advanced pancreatic cancer in-patients were divided into two groups

Chinese medicine group （n=32） and chemotherapy group（n=28）.Clinical conditions were comparable between the two groups（P>0.05）.The objective effective rate

overall survival period

progression-free survival period and adverse effects of the medicine were analyzed and compared.Results:PR was 0

SD 53.1% and PD 46.9% in the Chinese medicine group

and PR7.1%

SD 53.6%

and PD 39.3% in the chemotherapy group

with no significant difference between the two groups（P>0.05）.In the Chinese medicine group

the one-year survival rate was 34.37% and the median survival period was 6.07 months

that was better than 11.25% and 4.17months in the chemotherapy group（P<0.05）.Toxicity in the Chinese medicine group was less than the chemotherapy group.Conclusion:Chinese medicine may benefit to advanced pancreatic cancer patient by stabilizing tumors and prolonging life expectancy

with less side effects than that of chemotherapy.