Qiao Mingqi, Zhang Huiyun, Yu Yanhong, et al. Dynamic Changes of Serum Estradiol and Progesterone Levels in the Patient of Premenstrual Syndrome with Invasion of the Hyperactive Liver-qi[J]. Journal of Traditional Chinese Medicine2006, (4): 295-297.
Qiao Mingqi, Zhang Huiyun, Yu Yanhong, et al. Dynamic Changes of Serum Estradiol and Progesterone Levels in the Patient of Premenstrual Syndrome with Invasion of the Hyperactive Liver-qi[J]. Journal of Traditional Chinese Medicine2006, (4): 295-297.DOI: 10.13288/j.11-2166/r.2006.04.033.
Objective:To probe into the role of changes of ovarian hormones in pathogenesis of the specific subgroup of prementrual syndrome(PMS) and reveal partial microcosmic mechanisms of invasion of the hyperative liver-qi.Methods:Radioimmunoassay was used to determine dynamic changes of estradiol(E
2
) and progesterone (P) levels at different stages of menstrual cycle.Results:In the group of invasion of the hyperactive liver-qi
the secretive peak value of E
2
and P in the follicular phase decreased significantly
and the secretive peak value at the luteal phase did not form.Conclusion:Low E
2
and P secretive peak at the follicular phase and lack of secretive peak at the luteal phase is one of the micro-mechanisms of PMS with invasion of the hyperactive liver-qi.Continuous Lower level of E
2
and P is possibly a pathophysiolocal characteristics of special subgroup of PMS.