Objective:To observe efficacy of Weichangshu in treatment of diabetic gastroparesis（DGP）.Methods:96 cases of DGP conformed with the criteria were randomly divided into two groups.They were treated by oral administration of Weichangshu and Mosapride respectively for 4 weeks in addition to original treatment program for controlling blood sugar.Changes of clinical symptoms

FBG and P2hBG

gastric antrum-duodenum interdigestive period migrating motion compound wave（MMC）and electrogastrogram（EGG）before and after treatment were investigated.Results:Clinical symptoms were significantly improved in both groups.The markedly effective rate was 62.50% and the total effective rate was 91.67% in the Weichangshu group

and the corresponding index was 60.42% and 89.58% in the Mosapride group.After treatment

MMC significantly improved in both groups

with significant differences in lasting time of phase Ⅱ

and phase Ⅲ

and the contraction amplitude as compared with those before treatment（P<0.05）.EGG main frequency ratio was increased and the EGG main power ratio was strengthened with significant differences as compared with those before treatment（P<0.05 or P<0.01）.P2hBG decreased in the Weichangshu group.Conclusion:Weichangshu can significantly improve clinical symptoms

MMC and electric activity of the stomach

decrease postprandial blood sugar in the patient of DGP.It is an effective prescription for DGP.