Objective:To explore clinical therapeutic effect and safety of Bushen Qiangdu Recipe on ankylosing spondylitis（AS）.Methods:259 out-patients and in-patients enrolled were treated with Bushen Qiangdu Recipe for 6 months

one dose each day for oral administration in morning and night.BAS-G

BASDAI

BASFI

Likert’ 4-grade score of spinal pain

Likert’ 4-grade score of whole body pain

duration of morning stiffness

evaluation of doctor

the occiput-wall distance

the finger-floor distance

the mandible-stermum distance

chest expansion

Schober’ test

the range of spinal movement

Gaenslen’s sign

ESR

CRP

blood and urine routine examination

renal and hepatic functions were detected before and after treatment.Results:Significant improvement was observed in all indexes except for the occiput-wall distance and the mandible-stermum distance

and no adverse effect in blood and urine routine examination and renal and hepatic function was found.Conclusion:Bushen Qiangdu Recipe has therapeutic effect on ankylosing spondylitis.