Objective:To observe effects of Erzhi Tiangui Granules on the patient of infertility with both kidney Qi and Yin deficiency

and to evaluate its effect on quality of oocytes

the number of high-quality ovum

fertilized ovum and high-quality embryo

and the clinical pregnancy rate.Methods:Patients of the treatment group were treated with promoting ovulation program and oral administration of Erzhi Tiangui Granules

and the control group with simple the promoting ovulation program.Changes of symptoms of both kidney Qi and Yin deficiency

the number of mature oocytes

the high-quality ova

fertilization rate

high-quality embryos rate

pregnancy rate and dose of gonadotropin（Gn） before and after treatment were observed

and the correlative analysis was conducted.Results:The treatment group was significantly superior to the control group in improvement of the symptoms of both kidney Qi and Yin deficiency

high-quality oocytes rate

fertility rate

high-quality embryos rate and clinical pregnancy rate

and Gn dose in the treatment group was significantly lower than that in the control group.Improvement of symptoms of both kidney Qi and Yin deficiency was positively correlated with high-quality oocytes rate.Conclusion:Erzhi Tiangui Granules can significantly improve symptoms of both kidney Qi and Yin deficiency

increase high-quality oocytes

high-quality embryo and the clinical pregnancy rate.