Li Jun1, He Liqun2, Li Yi2. Effects of Fuzheng Huoxue Recipe on Blood Growth Hormone and Insulin Growth Factor in Chronic Renal Failure Rats[J]. Journal of Traditional Chinese Medicine2006, (6): 456-458.
Li Jun1, He Liqun2, Li Yi2. Effects of Fuzheng Huoxue Recipe on Blood Growth Hormone and Insulin Growth Factor in Chronic Renal Failure Rats[J]. Journal of Traditional Chinese Medicine2006, (6): 456-458.DOI: 10.13288/j.11-2166/r.2006.06.040.
Objective:To observe effects of Fuzheng Huoxue Recipe on blood growth hormone (GH) and insulin growth factor(IGF-1) in chronic renal failure(CRF) rats.Methods:Platt method was adopted to make 5/6 kidney excision CRF model rat
and the rats were divided into model group
Huangqi group
Enalapril group
Danshen group
Fuzheng Huoxue Recipe group and normal control group according to the blood creatinine level after modeling.Effects of Fuzheng Huoxue Recipe on GH and IGF-1 levels in CRF rats with large quantity of urinal protein were investigated.Results:GH and IGF-1 levels in the model control group were significantly higher than that in normal control group
and after treatment of Fuzheng Huoxue Recipe
blood GH and IGF-1 levels were significantly decreased.Conclusion:Fuzheng Huoxue Recipe can decrease blood GH and IGF-1 levels in CRF rats