Ruan Xiaofen, Jiang Meixian, Xu Yan, et al. Effects of Addition of Kanlijian on Exercise Tolerance,Quality of Life and Worsened Times in the Patient of Chronic Heart Failure[J]. Journal of Traditional Chinese Medicine2006, (7): 505-508.
Ruan Xiaofen, Jiang Meixian, Xu Yan, et al. Effects of Addition of Kanlijian on Exercise Tolerance,Quality of Life and Worsened Times in the Patient of Chronic Heart Failure[J]. Journal of Traditional Chinese Medicine2006, (7): 505-508.DOI: 10.13288/j.11-2166/r.2006.07.018.
Objective:To observe effects of addition of Kanlijian on exercise tolerance
quality of life and worsened times in the patient of chronic heart failure(CHF).Methods:60 cases of CHF with yang-deficiency of both the heart and the kidney were divided into a Kanlijian group (n=39) and a control group(n=21).The groups were treated routinely with western medicine
with Kanlijian added in the Kanlijian group.The treatment course was 24 weeks.6-minute walking test(6MWT)
quality of life(LHFQ) scale
NYHA grading
score for symptoms and signs of TCM
and ratio of withdrawal or reduction of diuretic and digoxin before and 4
8
12
24
48 weeks after treatment were investigated.Worsened times of heart failure in one year was calculated.Results:The Kanlijian group was superior to the control group in the therapeutic effect on TCM syndromes
6MWT
LHFQ scale
score for symptoms and signs of TCM and NYHA grading.For hemodynamic indexes
there was no significant difference in FS and E/A ratio between the two groups.After treatment
left ventricle ejection fraction(LVEF) significantly increased in Kanlijian group and no significant change was found in the control group;After treatment with addition of Kanlijian
dosages of diuretic and digoxin decreased significantly.Conclusion:Addition of Kanlijian to western medicine can significantly increase LHFQ
exercise tolerance and heart function
and reduce dosage of diuretic and digoxin
as well as the times of readmission to hospital due to acute aggravation of heart failure in the patient of CHF.