Li Fufeng, Zhuang Yanhong, Wang Yiqin, et al. Correlative Factors of Child Lingua Geographica Formation and the Immunological Mechanism[J]. Journal of Traditional Chinese Medicine2006, (7): 531-534.
Li Fufeng, Zhuang Yanhong, Wang Yiqin, et al. Correlative Factors of Child Lingua Geographica Formation and the Immunological Mechanism[J]. Journal of Traditional Chinese Medicine2006, (7): 531-534.DOI: 10.13288/j.11-2166/r.2006.07.032.
Objective:To approach to main correlative factors of child lingua geographica formation and the immunological mechanism.Methods:1562 children were surveyed with clinical epidemiological method
and flow cytometry was used to determin T- and B-lymphocyte subgroups and expression of cell chemotactic factor receptor-3(CCR3) and cell chemotoctic factor receptor-5(CCR5).Results:The main correlative factors of child lingua geographica formation were anaphylaxis
asthma history
infection
congenital constitution.The levels of T- and B-lymphocyte subgroups
CCR3 and interlukin-4 in the lingua geographica group were higher than that in the non-lingua geographica group and the control group(P<0.05).Conclusion:Formation of child lingua geographica is closely related with anaphylaxis
asthma history
infection and congenital constitution
and the changes of T- and B-lymphocyte subgroups provide an objective basis for immunological mechanisms of child lingua geographica formation.