Objective: To evaluate the therapeutic effect and safety of Qiancao Naomaitong Oral Liquid for acute ischemic stroke. Methods: 180 cases of acute ischemic stroke were randomly divided into treatment group （n=90） and control group （n=90）. Routine treatment was used in the control group

while Qiancao Naomaitong Oral Liquid was added in the treatment group. The therapeutic effect was evaluated by neurologic deficit score （NDS）

activities of daily living （ADL）

mini-mental state examination （MMSE） and center for epidemiological survey depression scale （CES-D） after 2 and 4 weeks of treatment respectively. Hemorheologic test was conducted on 40 patients in each group before and after 4 weeks of treatment. Results: After 4 weeks of treatment

the efficiency of treatment group was significantly higher than that of control group（P<0.05）; MMSE scores increased significantly

while platelet aggregation rate

plasma viscosity and fibrinogen decreased significantly in the treatment group （P<0.05）; impaired rate of ADL decreased significantly in the treatment group and was lower than that in the control group as well （P<0.05）. Conclusion: Qiancao Naomaitong Oral Liquid can reduce NDS

improve cognitive function

daily living ability

emotional state and hemorheologic indexes for acute ischemic stroke.