Objective To study the therapeutic effect and mechanism of Jiangtang Mixture combined with ear acupuncture for type 2 diabetic insulin resistance（IR）.Methods Totally 120 cases of type 2 diabetic IR were randomly and equally divided into western medicine（Metformin） group

Chinese medicine （Jiangtang Mixture） group and Chinese medicine with ear acupuncture group.The treatment lasted for one month.The therapeutic effect

fasting plasma glucose（FPG）

fasting insulin（FINS）

postprandial 2 hours plasma glucose（P2hPG）

hemoglobin A1c（HbA1c）

blood fat

insulin Sensitivity index（ISI） and insulin resistance index（IRI） were observed before and after treatment.Results The total effective rate in Chinese medicine with ear acupuncture group was 92.5%

which was superior to those in Chinese medicine group （P<0.05） and western medicine group （P<0.01）.There were significantly differences in symptoms

signs

pattern integrals

blood glucose

HbA1c blood fat

FINS

ISI and IRI between Chinese medicine with ear acupuncture group and other two groups after treatment（P<0.05 or P<0.01）.Conclusion Jiangtang Mixture combined with ear acupuncture can relieve IR obviously and cure type 2 diabetic IR effectively.