WANG You-qing, YE Zi. Effect of Tongfu Qingxia Decoction on Barrier Function of Intestinal Tract in Acute Pancreatitis Patients[J]. Journal of Traditional Chinese Medicine2007, (4): 325-327.
WANG You-qing, YE Zi. Effect of Tongfu Qingxia Decoction on Barrier Function of Intestinal Tract in Acute Pancreatitis Patients[J]. Journal of Traditional Chinese Medicine2007, (4): 325-327.DOI: 10.13288/j.11-2166/r.2007.04.017.
Objective To study the effect of Tongfu Qingxia Decoction on the barrier function and inflammatory reaction regulation of intestinal mucosa in acute pancreatitis patients.Methods Patients selected were randomly divided into two groups.Routine treatment was conducted in control group
while Tongfu Qingxia Decoction was added in treatment group.Plasmic endotoxin
tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)were observed before and after treatment.Results After treatment
plasmic endotoxin
TNF-α and IL-6 decreased and interleukin-2 increased significantly in both groups(P<0.05)
especially in treatment group(P<0.05).Conclusion In comparison with simple western treatment
the combination of Tongfu Qingxia Decoction can regulate immune function
relieve acute inflammatory reaction
decrease the level of TNF-α and endotoxin
improve internal environment and promote the relief and rehabilitation from AP obviously.