天麻钩藤饮合卡托普利对高血压病患者血压及炎症因子的影响

王强; 黎芳; 方显明

doi:10.13288/j.11-2166/r.2008.01.052

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天麻钩藤饮合卡托普利对高血压病患者血压及炎症因子的影响

临床研究 | 更新时间：2021-11-17

- 天麻钩藤饮合卡托普利对高血压病患者血压及炎症因子的影响
- Effect of Tianma Gouteng Decoction and Captoprii on Blood Pressure and Inflammatory Factor in Patients with Essential Hyperten-sion
- 中医杂志 2008年第1期页码：32-34
- 作者机构：
  
  1. 广西中医学院瑞康医院心内科
  2. 广西中医学院南宁市华东路10号
  3. ,530011
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2008.01.052
  中图分类号： R544.1
- 纸质出版：2008
- 稿件说明：
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[1]王强,黎芳,方显明.天麻钩藤饮合卡托普利对高血压病患者血压及炎症因子的影响[J].中医杂志,2008(01):32-34.

WANG Qiang LI Fang FANG Xianming. Effect of Tianma Gouteng Decoction and Captoprii on Blood Pressure and Inflammatory Factor in Patients with Essential Hyperten-sion[J]. Journal of Traditional Chinese Medicine2008, (1): 32-34.
[1]王强,黎芳,方显明.天麻钩藤饮合卡托普利对高血压病患者血压及炎症因子的影响[J].中医杂志,2008(01):32-34. DOI： 10.13288/j.11-2166/r.2008.01.052.

WANG Qiang LI Fang FANG Xianming. Effect of Tianma Gouteng Decoction and Captoprii on Blood Pressure and Inflammatory Factor in Patients with Essential Hyperten-sion[J]. Journal of Traditional Chinese Medicine2008, (1): 32-34. DOI： 10.13288/j.11-2166/r.2008.01.052.

摘要

目的探讨天麻钩藤饮联合卡托普利对老年性肝阳上亢型高血压病（EH）患者血压的作用及其机制。方法将80例EH患者随机分为两组。治疗组40例

服用天麻钩藤饮和卡托普利;对照组40例

服用卡托普利

4周为1个疗程。治疗前后检测患者的血压、血清超敏C反应蛋白（hs-CRP）、肿瘤坏死因子α（TNF-α）、白细胞介素-6（IL-6）。结果治疗后

治疗组降压疗效及症状疗效均优于对照组

差异具有统计学意义（P<0.05）。治疗组患者血清hs-CRP、TNF-α、IL-6浓度显著下降（P<0.05）。结论天麻钩藤饮联合卡托普利可降低老年性肝阳上亢型EH患者血压、血清hs-CRP、TNF-α及IL-6浓度

效果优于单纯应用卡托普利。

Abstract

Objective To investigate the effect of Tianma Gouteng Decoction and Captopril on blood pressure and its mechanism in the senile patients with essential hypertension（EH） in the pattern of ascendant liver yang.Methods Eighty cases with EH were ran- domly divided into two groups

with 40 cases in each group.Treatment group was given Tianma Gouteng Decoction and Captopril and the control group was given only Captopril.The treatment was lasted for 4 weeks.Observed were the changes in blood pressure and serum hs-CRP

TNF-αand IL-6.Results There was significant difference in blood pressure change and improvement of clinical symptoms after treatment between the two groups.The level of serum hs-CRP

TNF-αand IL-6 decreased significantly in the treat- ment group.Conclusion Tianma Gouteng Decoction and captopril can decrease blood pressure and serum hs-CRP

TNF-αand IL-6

and the effect was superior to captopril simply.

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