Objective To evaluate the effect and safety of Xiaoyin Ointment for blood-heat syndrome of psoriasis and to study further its effect on single symptoms of psoriasis such as erythema

scale

infiltration

pruritus and lesion area. Methods The 99 selected patients were randomized into 3 groups and were treated by Xiaoyin Ointment

Shidu （Damp and toxin removal） Ointment

and Vaseline Ointment respectively for 8 weeks. All patients of 3 groups took the Keyin Yifang （First prescription for psoriasis） as the basic medication. After treatment

the general effect and the effect on skin lesion were evaluated objectively

and the time-effect indices and the safety were assessed as well. Results The total effective rate（93.9%） of Xiaoyin Ointment on blood-heat syndrome was significantly superior to that of Shidu Ointment （78.8%

P<0.05）. As to the improvement of single symptoms

the function of Xiaoyin Ointment was stronger in removing scales and decreasing infiltration and quicker in relieving erythema than that of Shidu Ointment. There was no stimulation for skin and other untoward reactions discovered in application of Xiaoyin Ointment. Conclusion Xiaoyin Ointment can effectively improve the skin lesion of blood-heat syndrome of psoriasis

with low relapse rate and no obvious untoward reactions.