Objective To observe the effect and safety of Suhuang Zhike Capsule on cough variant asthma（CVA）.Methods In the multi-centered randomized controlled double-blinded clinical study

279 CVA cases were divided into the treatment group treated by Suhuang Zhike Capsule（196 of 209 cases completed the treatment）

and the control group treated by Zhike Ningsou Capsule（69 of 70 cases completed the treatment）.The treatment course was 2 weeks.The improvement in TCM symptoms

lung function and bronchial challenge test were observed.Results On the total effect

in the treatment group

the total effective rate was 90.31 % and the curative rate 61.22%;in the control group

the total effective rate was 72.46 % and the curative rate 36.23%.The former was superior to the latter（P<0.05）.On the comprehensive effect of TCM symptoms

in the treatment group

the total effective rate was 91.84 % and the curative rate 62.76%;in the control group

the total effective rate was 81.16 % and the curative rate 27.54%.The former was superior to the latter（P<0.05）.After treatment

the bronchial challenge test in some cases of the treatment group changed to negative

showing a significant difference from the control group（P<0.05）.Conclusion Suhuang Zhike Capsule has an obvious therapeutic effect on CVA by reducing the bronchial reaction of patient.