LIU Gui-ying, ZHANG Yun-zhuo, WANG Zhao-jie, et al. Effect of Kechuan Capsule on 15 Cases of Bronchial Asthma at Persistent Stage[J]. Journal of Traditional Chinese Medicine2008, (7): 611-613.
LIU Gui-ying, ZHANG Yun-zhuo, WANG Zhao-jie, et al. Effect of Kechuan Capsule on 15 Cases of Bronchial Asthma at Persistent Stage[J]. Journal of Traditional Chinese Medicine2008, (7): 611-613.DOI: 10.13288/j.11-2166/r.2008.07.013.
Objective To observe the effect of Kechuan Capsule on the syndrome of wind-phlegm retention in lung at the persistent stage of bronchial asthma.Methods Totally 35 cases were randomly divided into treatment group(18 cases)and control group(17 cases)
and 15 cases of each group completed the study.Patients in the treatment group were administrated Kechuan Capsule
4 capsules each time
3 times a day;while those in the control group inhaled budesonide 200μg each time
twice a day.The course of treatment was 28 days.The effect on asthma episode
main symptoms
forced expiratory volume in 1 second(FEV1)
peak expiratory flow rate(PEFR)and variation rate of PEF in 24 hours were observed.Results The effective rate of the treatment group was 60.0% while that of control group 66.7%
without significant difference between two groups(P>0.05).In relieving wheeze
the effective rate of both groups was the same
73.3%.In reliving chest distress
the effective rate of treatment group was 73.3% and that of control group 33.3%
with a significant difference(P<0.05).FEV1 and PEFR of lung function of both groups were improved significantly after treatment(P<0.05)
but no significant difference was found between groups(P>0.05).The variation rate of PEF of two groups in 24 hours were significantly different in in-group and between-group comparisons(P<0.05).Conclusion Kechuan Capsule can relieve the symptoms of wind-phlegm retention in lung of bronchial asthma at persistent stage
improve the lung function in respiration and inhibit the episode of asthma.The treatment group was superior to the control group in relieving chest distress and decreasing variation rate of PEF in 24 hours.