Objective To observe the effect of the reinforcing kidney

nourishing and activating blood on promoting ovulation and improving the endometrium thickness and pregnancy rate in the process of in vitro fertilization-embryo transplantation（IVF-ET）.Methods The 63 cases receiving IVF-ET were randomly divided into two groups: the treatment group（n=31） treated with GnRHa/r-FSH/HMG/HCG combined with the herbs of kidney-reinforcing

blood-nourishing and blood-activating in different periods of IVF-ET

and the control group（n=32） with GnRHa/ r-FSH/HMG/HCG alone.The dose of gonadotropin（Gn）

endometrium thickness

follicular oocyte number

high-quality oocyte rate

fertilization rate

high-quality embryo rate and pregnancy rate of both groups were observed.Results In the treatment group

Gn dose was significantly lower（P<0.01） and endometrium thickness increased（P<0.05）

and the effect on increasing the high-quality oocyte rate

fertilization rate

high-quality embryo rate

and pregnancy rate was better than that in the control group（P<0.05）.Conclusion The therapy of replenishing kidney

nourishing and activating blood is effective in promoting ovulation

increasing endometrium thickness

and helping embryo implantation.In combination with IVF-ET

it increases the pregnancy rate

serving as an effective treatment for infertile women.