青陈合剂对脾虚气滞型糖尿病胃轻瘫患者血浆胃动素及体表胃电图的影响

骆天炯; 徐小萍; 孙丽霞; 胡刚; 徐陆周; 赵乐天; 周斌; 章金春; 王雁君; 贾晓峰

doi:10.13288/j.11-2166/r.2009.02.012

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青陈合剂对脾虚气滞型糖尿病胃轻瘫患者血浆胃动素及体表胃电图的影响

临床研究 | 更新时间：2021-11-17

- 青陈合剂对脾虚气滞型糖尿病胃轻瘫患者血浆胃动素及体表胃电图的影响
- Clinical Observation on the Treatment of Diabetic Gastroparesis of Spleen Deficiency and Qi Stagnation Syndrome by Qingchen Mixture
- 中医杂志 2009年50卷第2期页码：130-132
- 作者机构：
  
  1. 南京市中医院
  2. 江苏省中医院
  3. 南京中医药大学
- 作者简介：
- 基金信息：
  
  南京市科技局社会发展计划资助项目（2005指导0504）
- DOI：10.13288/j.11-2166/r.2009.02.012
  中图分类号： R259
- 纸质出版：2009
- 稿件说明：
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[1]骆天炯,徐小萍,孙丽霞,胡刚,徐陆周,赵乐天,周斌,章金春,王雁君,贾晓峰.青陈合剂对脾虚气滞型糖尿病胃轻瘫患者血浆胃动素及体表胃电图的影响[J].中医杂志,2009,50(02):130-132+149.

LUO Tianjiong1, XU Xiaoping2, SUN Lixia3, et al. Clinical Observation on the Treatment of Diabetic Gastroparesis of Spleen Deficiency and Qi Stagnation Syndrome by Qingchen Mixture[J]. Journal of Traditional Chinese Medicine2009, 50(2): 130-132.
[1]骆天炯,徐小萍,孙丽霞,胡刚,徐陆周,赵乐天,周斌,章金春,王雁君,贾晓峰.青陈合剂对脾虚气滞型糖尿病胃轻瘫患者血浆胃动素及体表胃电图的影响[J].中医杂志,2009,50(02):130-132+149. DOI： 10.13288/j.11-2166/r.2009.02.012.

LUO Tianjiong1, XU Xiaoping2, SUN Lixia3, et al. Clinical Observation on the Treatment of Diabetic Gastroparesis of Spleen Deficiency and Qi Stagnation Syndrome by Qingchen Mixture[J]. Journal of Traditional Chinese Medicine2009, 50(2): 130-132. DOI： 10.13288/j.11-2166/r.2009.02.012.

摘要

目的观察青陈合剂对脾虚气滞型糖尿病胃轻瘫患者胃动力的影响。方法将60例脾虚气滞型糖尿病胃轻瘫患者随机分为试验组和对照组各30例

试验组口服中药青陈合剂每次20ml

每日3次;对照组口服吗丁啉每次10mg

每日3次。治疗30天后观察两组服药前后症状积分、血浆胃动素、体表胃电图的动态改变。结果试验组总有效率93.33%

对照组总有效率73.33%

两组疗效比较差异有统计学意义（P<0.05）。试验组在降低胃动过缓率、改善餐后胃电节律等方面与对照组比较差异有统计学意义（P<0.05）。结论青陈合剂能有效调节脾虚气滞型糖尿病胃轻瘫患者胃肠激素、增强胃蠕动、改善胃电节律、促进胃排空。

Abstract

Objective To observe the effect of Qingchen Mixture on the plasma motilin and electrogastrograph of diabetic gastroparesis（DGP） patients in spleen deficiency and qi stagnation syndrome.Methods The 60 DGP patients in spleen-deficiency and qi-stagnation syndrome were randomized into the trail group

treated by Qingchen Mixture

3 times a day

20ml each time

and the control group

treated by Domperidone

3 times a day

10ml each time.After 30 days

the scores of clinic symptoms

plasma motilin and the electro-gastrogram（EGG） were observed for comparing with those before treatment.Results The total effective rate of trail group was 93.33% while that of the control group was 73.33%

the difference was significant（P<0.05）.In decreasing the slow gastric motion rate and improving gastric electric rhythm

the difference between the two groups was significant（P<0.05）.Conclusion The Chinese medicine Qingchen Mixture can regulate gastrointestinal hormone

strengthen gastric wriggle

improve electro-gastric rhythm

and accelerate gastric emptying.

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