Objective To assess the effect of acupuncture on chronic urticaria （CU） and to analyze the present situation of clinical researches. Methods The data of randomized controlled trials of acupuncture for treatment of CU were collected by retrieval tools PubMed

EMBASE

OVID

Cochrane library

CBM database

and CNKI database

and the quality was assessed with Cochrane Reviewer’s Handbook. Results Totally 12 literatures entered the research

altogether 983 cases. Meta analysis showed that the difference between the groups of acupuncture and western medicine treatment was significant; the difference between the groups of acupuncture plus western medicine and western medicine treatment was significant; and the difference between the groups of acupuncture plus antihistamine drugs and only antihistamine drugs treatment was significant in recurrence rate. Conclusion acupuncture is effective and safe for CU. The effect of acupuncture plus drugs is better than that of treatment only with drug. The recurrence rate is lower when antihistamine drugs are used in combination with acupuncture. But because the entered literatures are not enough in quantity and some of them are low in quality

therefore the high quality evidence is needed for the further definite conclusion.