Objective To observe the effect of Jinhua Weikang Pill on epidermal growth factor（EGF） and basic fibroblast growth factor（bFGF） of gastric mucosa in rats with gastric ulcers.Methods Of the 32 Wistar rats

8 as the normal control group

24 were made gastric ulcer model by dropping acetic acid on the surface of their gastric mucous and randomized into model control group

Jinhua Weikang Pill group

and sucralfate group

8 rats in each.The medication was given respectively for 10 days in succession.Then

the quantitative detection was done to see the changes of content of EGF and bFGF in the gastric mucous around the ulcers.Results Compared with the normal control group

EGF and bFGF content in model control was significantly higher（P<0.01）.Compared with the model control group

EGF and bFGF content in Jinhua Weikang Pill group decreased significantly（P<0.05）.Compared with the normal control group and sucralfate group

EGF and bFGF content in Jinhua Weikang Pill group was not different（P>0.05）.Conclusion Jinhua Weikang Pill promotes the healing of damaged mucosa through regulating the content of EGF and bFGF of gastric tissues

which is possibly part of the mechanism in healing the gastric mucosa.