LIU Huan1, CHEN Biao2. Study on TCM Syndromes of Parkinson’s Disease[J]. Journal of Traditional Chinese Medicine2009, 50(8): 728-729.DOI: 10.13288/j.11-2166/r.2009.08.013.
Objective To investigate the distribution of TCM Syndromes of Parkinson’s disease(PD).Methods The 125 PD patients were graded according to Hoehn-Yahr(H
&
Y) criteria for assessment.The assigned TCM physician investigated TCM syndromes of these patients with the structured questionnaire which was based on literature and experience of experts.Results Of 125 cases
96 ones(76.8%) presented a single syndrome
and 29 ones(23.2%) presented complex syndrome.The positive rate of main syndrome was in an order of deficiency of both the Spleen and Kidney(22.4%)
yin deficiency of the Liver and Kidney(18.4%)
yang deficiency of the Spleen and Kidney(16%)
qi deficiency of both qi and yin(15.2%)
phlegm-heat stirring up the wind(12.8%)
qi deficiency with blood stasis(4.8%)
deficiency of both yin and yang(4%)
damp abundance due to the Spleen deficiency(3.2%)
endoretention of damp heat(1.6%)
stagnation of the Liver qi with deficiency of the Spleen and Liver fire flaring(0.8%).There existed a significant difference in the distribution of TCM syndromes in H
&
Y 1.0
1
.5 and H
&
Y 2.0
3
.0(P
<
0.05).Conclusion The pathogenesis of PD patients in early stage is mainly yin deficiency of both the Liver and Kidney
with abundant phlegm heat and blood stasis;in middle stage it was mainly deficiency of both the Spleen and Kidney
with phlegm damp retention;while in late stage it was mainly qi deficiency and yang deficiency
which later developed into deficiency of both yin and yang.