LIU Linlin, GUO Rongjuan, ZHANG Yunling, et al. Relations among Phlegm Turbidity,Blood Stasis Syndromes,Interleukin-6 and High-Sensitive C-Reactive Protein in Hypertension Patients[J]. Journal of Traditional Chinese Medicine2010, 51(2): 122-124.
LIU Linlin, GUO Rongjuan, ZHANG Yunling, et al. Relations among Phlegm Turbidity,Blood Stasis Syndromes,Interleukin-6 and High-Sensitive C-Reactive Protein in Hypertension Patients[J]. Journal of Traditional Chinese Medicine2010, 51(2): 122-124.DOI: 10.13288/j.11-2166/r.2010.02.030.
Objective To study the relations among phlegm turbidity
blood stasis syndromes
Interleukin-6 (IL-6) and highly sensitive C-reactive protein (hs-CRP) in simple hypertension patients and those complicated with abnormal blood fat and/or diabetes.Methods Totally 319 cases of hypertension collected were divided into the group with simple hypertension (simple group
98 cases) and the group with hypertension complicated with abnormal blood fat and/or diabetes (complicated group
221 cases). The patients were classified according to the 4 different syndromes
i.e.
phlegm turbidity
blood stasis
phlegm turbidity plus blood stasis
and not phlegm turbidity not blood stasis. ELISA was used to measure serum IL-6 content
and latex enhancement immune turbidimetry was applied to determine hs-CRP content.Results The contents of IL-6 and hs-CRP of the two groups were not significantly different. The content of hs-CRP of both groups in the 4 syndromes was not significantly different. In the simple group
the content of IL-6 in the 4 syndromes was not significantly different either. In the complicated group
the content of IL-6 in the syndrome of phlegm turbidity plus blood stasis was significantly higher than in other syndromes (P<0.05 or P<0.01)
while the content of IL-6 in other syndromes was not significantly different.Conclusion The hypertension complicated with abnormal blood fat and/or diabetes is always manifested as the syndrome of phlegm turbidity and blood stasis
which is probably related with the high level of IL-6.