YANG Minchun, ZHANG Zhaocai, CAI Guolong, et al. Correlation Between Endotheliocyte Function,Inflammation-Related Factors and TCM Syndromes in Sepsis Patients[J]. Journal of Traditional Chinese Medicine2010, 51(3): 253-255.
YANG Minchun, ZHANG Zhaocai, CAI Guolong, et al. Correlation Between Endotheliocyte Function,Inflammation-Related Factors and TCM Syndromes in Sepsis Patients[J]. Journal of Traditional Chinese Medicine2010, 51(3): 253-255.DOI: 10.13288/j.11-2166/r.2010.03.009.
Objective To study dynamically the correlation between endotheliocyte functions
inflammation-related factors and TCM syndromes in sepsis patients.Methods According to the TCM syndrome differentiation
68 septic patients were divided into Qi-fen group (23 cases)
Ying-fen group (28 cases)
and Xue-fen group (17 cases).The control group (26 cases) was built up for contrast.Serum von willebrand factor (vWf)
nitric oxide (NO)
tumor necrosis factor-α (TNF-α)
interleukin 6 (IL-6)
interleukin 2(IL-2)
interleukin 4 (IL-4)
and white blood cell (WBC) count of all groups were measured.Results TNF-α
IL-6
and WBC in all the sepsis groups were significantly higher than those in the control group (P<0.05 or P<0.01).IL-4 in the Ying-fen group and Xue-fen groups was increased (P<0.01 or P<0.05).The vWf and NO in the Xue-fen group were higher than those in the control group (P<0.05 or P<0.01).Comparison in the sepsis groups showed that NO in the Xue-fen group was significantly higher than that in the Qi-fen group and Ying-fen groups (P<0.01);while vWf in the Xue-fen group was significantly higher than that in the Ying-fen group (P<0.01).Conclusion The level of vWf and NO of sepsis patients varies with the different TCM Syndromes.Dynamic observation on vWf and NO contributes to the TCM syndrome differentiation for sepsis.