Objective To observe the effect of Jiangtang Sanhuang Pill （Herbal pills for reducing blood glucose） in the treatment of metabolic syndrome in the type of heat and blood stasis stagnation. Methods Seventy-two cases were randomized into two groups

herb group （37 cases） and western medicine group （35 cases）

and on the basis of the same treatment of diet and physical exercises

the herb group received the Jiangtang Sanhuang Pill for purging heat

eliminating blood stasis

replenishing qi

and nourishing yin

while the western medicine group received Acarbose

the conventional western medicine treatment. The course of treatment was 2 months and the therapeutic effect

changes of blood pressure （BP）

body mass index （BMI）

waist hip ratio （WHR）

and total score of clinical symptoms

blood glucose

insulin

glycolated hemoglobin （HbA1c）

total cholesterol （TC）

triglyceride （TG）

high density lipoprotein cholesterol （HDL-C）

and low density lipoprotein cholesterol （LDL-C） of both groups were observed. Results The total effective rate of the herb group was 78.4%

while that of the western medicine group was 82.9%

the difference between was not significant （P>0.05）. The improvement in total score of symptoms of the herb group was better than that of the western medicine group （P<0.05）. The changes in BMI

WHR

and BP of both groups after treatment were not significant （P>0.05）. The blood glucose

HbA1c

and insulin of both groups was lowered after treatment （P<0.01 or P<0.05）. TC

TG and LDL-C of both groups were lowered after treatment （P<0.01 or P<0.05）. HDL-C of both groups was increased after treatment （P<0.01）. The improvement in TC and HDL-C of the western medicine group was superior to that of the herb group with a significant difference （P<0.01 or P<0.05）. Conclusion Jiangtang Sanhuang Pill is safe and effective for metabolic syndrome in the type of heat and blood stasis stagnation.