Objective To evaluate the clinical effect of Tiaoxie Wan（Chinese medicine for regulating the metabolic functions）on the metabolic syndrome.Methods Under the condition without changing their original treatment

the 62 metabolic syndrome patients were administered Tiaoxie Wan for oral taking in succession for 2 months.The blood lipid

glycolated hemoglobin（HbA1C）

fasting insulin（FINS）

insulin action index（IAI）

body mass index（BMI）

and the clinical effect of main symptoms were observed.Results After treatment

the symptoms such as dizziness

dry mouth

constipation

abdominal distention

and hot temper with irritability were significantly relieved

the total effective rate was all above 85%.The BMI

blood lipid

and HbA1C were significantly decreased

while the FINS and IAI were significantly increased（P<0.05 or P<0.01）.Conclusion Tiaoxie Wan is effective in improving the high blood lipid state of the patients with metabolic syndrome by increasing insulin secretion and improving insulin sensitivity.