Objective To evaluate the effect and safety of Chinese medicine for perianal eczema with the method of systematic review.Methods The database such as Pubmed

Cochrane library

CNKI

VIP

CBM and CMCI were consulted through internet.The quality evaluation standard of Cochrane Collaboration was adopted and the software RevMan 4.2 provided was used for the statistical analysis of the clinical total effective rate

symptom improvement

and untoward reactions of the trials involved.Results There were 32 randomized control trials（3429 patients）reviewed.All trials involved were of low quality.Of the 26 trials of Chinese medicine in comparison with western drugs

15 ones showed that the therapeutic effect of the experimental group was better than the control group

and 11 ones showed that there was no significant difference between the two groups.Of the 6 trials of Chinese medicine combined with western drugs in comparison with western drugs only

5 ones showed that the therapeutic effect of the experimental group was better than the control group

and one trial showed that there was no significant difference between the two groups.The comparison of intervention measures on the whole

the clinical total effective rate and symptom improvement of the Chinese medicine and Chinese medicine combined with western drugs were better than those of the western drugs only.There was no obvious adverse effect reported in the trials of Chinese medicine treatment.Conclusion Chinese medicine is effective in improving symptoms of eczema patients but methodology needs to be improved urgently.