WANG Hongdu1, FU Shijie1, CHEN Zhuang2, et al. The Antiosteoporotic Effect of Electroacupuncture at Foot Shaoyang Channel Points in Ovariectomized Rats[J]. Journal of Traditional Chinese Medicine2011, 52(4): 322-325.
WANG Hongdu1, FU Shijie1, CHEN Zhuang2, et al. The Antiosteoporotic Effect of Electroacupuncture at Foot Shaoyang Channel Points in Ovariectomized Rats[J]. Journal of Traditional Chinese Medicine2011, 52(4): 322-325.DOI: 10.13288/j.11-2166/r.2011.04.005.
Objective To verify the antiosteoporotic effect of electroacupuncture at Foot Shaoyang Channel points.Methods Forty Wistar female rats were randomized into sham operation group
model group
gall bladder channel point group
and non-channel point group
and the latter three groups were ovariectomized.Three months after operation
the gall bladder channel point group and non-channel point group were treated with electroacupuncture at the corresponding points according to the planned program for 3 months.Then the samples were collected for studying the changes in bone mineral density(BMD)
bone histomorphology
and bone biomarkers including bone formation and resorption indices.Results In the model group and non-channel point group
the BMD/body weight adjusted value were significantly lowered than those in the gall bladder channel point group and sham operation group(P<0.05).Bone tissue HE stained observation showed that the bone microstructure in the gall bladder channel point group was more significantly improved than that of other groups.Bone formation markers showed that the osteoblastic activity of remodeling was stronger in the gall bladder channel point group than that of other groups(P<0.05).Bone resorption markers also showed that the osteoclastic activity was stronger in the non-channel point group and model group than that of other groups(P<0.05).But bone resorption in the gall bladder channel point group was lowered
without statistical difference in comparing with the sham operation group(P>0.05).Conclusion Electroacupuncture at Foot Shaoyang Channel points is surely effective in antiosteoporosis
providing an experimental evidence for the theory in Internal Classic that Shaoyang dominates bones
from which
the inference is that the Shaoyang channel and its points can regulate the bone intensity