JIAN Yaping1, YUAN Zhaokai2. Clinical Observation on Yangxin Tongmai Tablets for Treatment of 32 Dyslipidemia Patients[J]. Journal of Traditional Chinese Medicine2011, 52(10): 862-864.
JIAN Yaping1, YUAN Zhaokai2. Clinical Observation on Yangxin Tongmai Tablets for Treatment of 32 Dyslipidemia Patients[J]. Journal of Traditional Chinese Medicine2011, 52(10): 862-864.DOI: 10.13288/j.11-2166/r.2011.10.015.
Objective To discuss the effect of Yangxin Tongmai Tablets (Herbal tablet for nourishing the heart and relieving stasis) on the principle of reinforcing qi
dissolving phlegm
removing obstruction and dissolving stasis for dyslipidemia patients. Methods Sixty-eight dyslipidemia patients with phlegm combining with blood stasis syndrome were randomized into treated group and control group. The treated group was administered Yangxin Tongmai Tablets
while the control group was prescribed Jiaogulan Zongdai Pian (Gynostemma pentaphyllum total glucoside tablet) for oral taking. The course of treatment was of one month. Before and after treatment
changes in total cholesterol (TC)
triglyceride (TG)
low density lipoprotein cholesterol (LDL-C)
and high density lipoprotein cholesterol (HDL-C) were observed to evaluate the therapeutic effect. Results Of the 32 patients in the treated group
there were 2 patients clinically controlled
18 patients remarkably effective
10 patients effective
2 patients ineffective
the total effective rate was 93.75%. Of the 21 patients in the control group
there was 1 patient clinically controlled
9 patients remarkably effective
8 patients effective
3 patients ineffective
and the total effective rate was 85.71%. The total effective rate of both groups was not statistically different (P>0.05). In both groups
the TC and LDL-C were significantly decreased while the HDL-C increased (P<0.05 or P<0.01). After treatment
the difference between the two groups was not statistically significant (P>0.05)
but there was still a significant decrease of TG in the treated group (P<0.05). Conclusion Yangxin Tongmai Tablets is effective in regulating the level of blood lipid
and the principle of reinforcing qi
dissolving phlegm
removing obstrction and dissolving stasis is an effective treatment for lipid metabolism disorders.