ZHANG Ya1, CHEN Hui2, LI Chandong3, et al. Influence of Syndrome of Qi Deficiency with Blood Stasis on the Anti-thrombosis Effect after Percutaneous Coronary Intervention[J]. Journal of Traditional Chinese Medicine2011, 52(10): 859-861.
ZHANG Ya1, CHEN Hui2, LI Chandong3, et al. Influence of Syndrome of Qi Deficiency with Blood Stasis on the Anti-thrombosis Effect after Percutaneous Coronary Intervention[J]. Journal of Traditional Chinese Medicine2011, 52(10): 859-861.DOI: 10.13288/j.11-2166/r.2011.10.031.
Objective To explore the independent risk factors for the major cardiovascular events (MCVE) after percutaneous coronary intervention (PCI). Methods Totally 123 coronary heart disease (CHD) patients successful treated by PCI were given standard anti-thrombosis treatment
and they were classified into the qi deficiency with blood stasis group (49 cases) and non-qi deficiency with blood stasis group (74 cases) according to TCM syndrome differentiation. Seven days later
all patients were examined with blood test to observe their platelet count
maximum platelet aggregation (MPA)
plasma hereditary false hemophilia factor vWF
platelet membranous glycoprotein Ⅱ b/Ⅲ a (GPⅡ b/Ⅲ a)
prothrombin fragment 1+2 (F1+2)
and fibrinogen (Fg). Using Logistic regression analysis to screen out the independent risk factors for MCVE one year after PCI. Results The MPA
vWF
and GPⅡb/Ⅲa of the qi deficiency with blood stasis group were higher than those of the non-qi deficiency with blood stasis group (P<0.05)
while the platelet count
F1+2
and Fg of the two groups were without statistical difference (P>0.05). Conclusion There still exists the obvious platelet activation and vascular endothelial injury in qi deficiency with blood stasis after PCI
. This is one of the independent risk factor for MCVE after PCI.