Objective Using mathematical statistics method to generalize the TCM syndromes of diabetic peripheral neuropathy（DPN） for studying the corresponding relations with the severity of pathological damage.Methods The data of 192 DPN cases were collected.After literature retrieval

46 TCM symptoms and signs were drafted and quantitatively assigned.The R-clustering and simple correspondence analysis were adopted for statistical inference.Results The interception at a proper location of clustering graph showed that the 46 TCM symptoms and signs were clustered into five basic syndromes

i.e.qi deficiency syndrome

yin deficiency syndrome

yang deficiency syndrome

obstruction of blood stasis syndrome

and retention of phlegm damp syndrome.The correspondence analysis showed that TCM syndromes and pathological severity were related with each other（χ2 = 30.752

P<0.01）.Qi deficiency syndrome was most closed to DPN levelⅠ（asymptomatic DPN）

yin deficiency syndrome most closed to DPN level Ⅱ（symptomatic DPN）

and yang syndrome most closed to DPN level Ⅲ（function affected DPN）.Obstruction of blood stasis syndrome and retention of phlegm damp syndrome were in the middle of projection graph

without very clear relation to a certain degree of DPN pathological severity.Conclusion Qi deficiency

yin deficiency

yang deficiency

obstruction of blood stasis

and retention of phlegm damp are the basic syndromes of DPN.Along with the progress of pathological damage

its TCM syndromes are also changed from qi deficiency

yin deficiency

to yang deficiency

while blood stasis and phlegm damp are existing throughout the whole process of DPN.