Objective To observe the effect of Yuepi Kaiwei Granule（Granule for activating the spleen to whet the appetite） on the infantile anorexia of spleen deficiency with food retention.Methods The enrolled patients were randomized into the treatment group（34 cases） and the control group（31 cases）.The treatment group orally took Yuepi Kaiwei Granule of the following dosage

i.e.

under the age of 1 year 7.5g each time

1 to 4 years old 10g

5 to 9 years old 15g

10 years old and older 20g

twice a day.The control group took orally Qipi Koufuye（Liquid for promoting the spleen） of the following dosage

i.e.

under the age of 1 year 3ml each time

1 to 4 years old 5ml

5 to 9 years old 7.5ml

10 years old and over 10ml

three times a day.Both groups were medicated for 14 days in succession.The total score of clinical symptoms and the scores of anorexia and reduce of appetite of children of both groups were evaluated before and after the treatment respectively.Results The total effective rate of the treatment group was 83.94% and that of the control group was 64.63%

the difference was significant（P<0.01）.The total score of clinical symptoms and the scores of anorexia and reduce of appetite of both groups were significantly reduced than those of before treatment（P<0.05 or P<0.01）

and after treatment the above mentioned scores were statistically different in comparison between the two groups（P<0.05）.Conclusion Yuepi Kaiwei Granule is effective in the treatment of infantile anorexia of spleen deficiency with food retention

better than Qipi Koufuye.