FAN Hua, XU Jixun, HUANG Jing, et al. Clinical Study on 40 Children Bronchial Asthma Cases Treated by Maxin Pingchuan Decoction[J]. Journal of Traditional Chinese Medicine2011, 52(13): 1112-1114.
FAN Hua, XU Jixun, HUANG Jing, et al. Clinical Study on 40 Children Bronchial Asthma Cases Treated by Maxin Pingchuan Decoction[J]. Journal of Traditional Chinese Medicine2011, 52(13): 1112-1114.DOI: 10.13288/j.11-2166/r.2011.13.010.
Objective To observe the therapeutic effect of Chinese medicine Maxin Pingchuan Decoction(Decoction including ephedra and asarum herb for stopping asthma)on children asthma.Methods Totally 120 hospitalized children with acute attack of asthma were randomized into Maxin Pingchuan Decoction group(Decoction group)
Easy Jotham Static control group(EJS group)
and Singulair control group(Singulair group)
with 40 patients in each.Three groups were all given aerosol inhalation and anti-infection as routine treatment in addition to Maxin Pingchuan Decoction
Easy Jotham Static
and Singulair for oral taking respectively.They were not given any other herbal or western medicines for asthma.The clinical effect of 3 groups was observed after 7 days treatment.Before and after treatment
peak expiratory flow(PEF)
forced expiratory volume in one second(FEV1)
immunoglobulin E(IgE)
interleukin 5(IL-5)and eosinophilic granulocyte count(EOS)were examinationed.Results Although the Decoction group was slightly better than EJS group and Singulair group in clinical controlling rate
the difference was not significant in statistics(P>0.05).After treatment
FEV1 and PEF of 3 groups were all increased and the difference was significant in statistics(P<0.01)
but there was no statistics difference among the 3 groups(P>0.05).EOS
IgE
and IL-5 of 3 groups were all decreased with a significant difference in statistics(P<0.01).The effect of EJS group and Singulair group on EOS
IgE
and IL-5 was significantly different as compared with the Decoction group(P<0.01).Conclusion Maxin Pingchuan Decoction is effectively improving the lung functions and controlling the asthma symptoms.