Objective To explore the effect and its mechanism of Taiyi moxa-cigar warming moxibustion on the local immune function of rats with sequela of pelvic infection.Methods The female Wistar rats were randomized into normal group

model group

experiment group

and control group

10 in each.The normal group and model group were conventionally raised.The experiment group and control group were treated with Taiyi moxa-cigar warming moxibustion and general moxibustion respectively at Guanyuan（CV 4）and Ciliao（BL 32）

30 minutes for each point each time

once a day.One month later

the morphological and pathological changes of uteri of rats of each group were observed and the uterine inflammatory severity was scored as well

and the content of secretary immunoglobulin A（S-IgA）

serum interleukin 6（IL-6）

and tumor necrosis factor α（TNF-α）in the vaginal rinsing water was detected.Results In the experiment group

the uterine cavity was basically unobstructed with a little effusion in it

the glandular structure was clear

and the glandular epithelium was mildly hyperplastic.Compared with the model group

the score of uterine inflammatory severity of the normal group

experiment group

and control group was statistically different（P<0.01）.And the score of the experiment group and control group was also statistically different（P<0.05）.Compared with the model group

the S-IgA content of experiment group was statistically different（P<0.01）.In the model group

the IL-6 and TNF-αcontent was significantly increased

compared with the other 3 groups

the statistical difference was significant（P<0.01 or P<0.05）.The TNF-αand IL-6 content of the experiment group was not statistically different from that of the control group（P>0.05）.Conclusion The occurrence of sequela of pelvic inflammation is related to the inadequacy of local S-IgA secretion

the weakening of regional immune function

and the abnormality of cell factors.Taiyi moxa-cigar warming moxibustion is able to regulate them to a certain degree.