WANG Zhengyi, HUANG Xiuhua, XIE Yike, et al. Influence of Kangfuxin Liquid on the Wound Healing of Experimental Animal Burns and Scalds[J]. Journal of Traditional Chinese Medicine2011, 52(15): 1316-1317.
WANG Zhengyi, HUANG Xiuhua, XIE Yike, et al. Influence of Kangfuxin Liquid on the Wound Healing of Experimental Animal Burns and Scalds[J]. Journal of Traditional Chinese Medicine2011, 52(15): 1316-1317.DOI: 10.13288/j.11-2166/r.2011.15.038.
Objective To study the influence of Kangfuxin Liquid(Liquid for healing the burns and scalds)on the experimental rat burns and rabbit scalds.Methods Forty SD rats and 24 rabbits
half male and half female
were evenly randomized into 4 groups
including model group
positive control group
and Kangfuxin Liquid low-dose and high-dose groups.Using alcohol burning method to make rat skin deep Ⅱ degree burn models and using punctuate scalding method to make rabbit skin deep Ⅱ degree scald models.The model group was applied normal saline externally
the positive control group was given ulfadiazine silver creame.Kangfuxin high-dose and low-dose group were given Kangfuxin Liquid of primary and half-concentration.Kangfuxin Liquid was applied to the wounded skin
3 times a day
14 days in succession.The healing of the wound was observed.Results From the fourth day of Kangfuxin Liquid application
the burned area of rat in high-dose group was significantly smaller than that of the model group(P<0.05).From the seventh day of Kangfuxin Liquid application
the burned area of rat in high-and low-dose groups was significantly smaller than that of the model group(P<0.05).From the tenth day of Kangfuxin Liquid application
the scalded area of rabbit in high-and low-dose groups was significantly smaller than that of the model group(P<0.05).The tissue repairing of both experiments was significantly better than that of the model group.Conclusion Kangfuxin Liquid is significantly improving the wound healing of rat burns and rabbit scalds.