Objective To explore the objectification of TCM spleen system questioning information based on a latent structure model.Methods Using a heuristic doubly hill-climbing method of latent structure to do automatic search

40 variables participating in analysis were selected from 1 310 spleen system samples transformed and recorded already for data analysis.The changes of Bayesian Information Criterion（BIC） score of models in the analysis process were observed.Results Of the TCM spleen system diseases in 1 310 cases

most were chronic superficial gastritis and chronic atrophic gastritis patients

occounted for 46.6℅ and 14.7℅ respectively.The initial model obtained was marked as M0.In the model M0 there were 12 latent variables and their BIC score was-20243.42806654384.Conclusion The latent structure model is in accordance with the syndrome characteristics of Chinese medicine theory and spleen system diseases

basically reflected the main etiology and pathogenesis of spleen system diseases

and provided the beneficial reference for the objectification studies on TCM questioning information.