Objective To observe the influence of detoxificating and activating b lood herbal medicine on inflammation reaction of the patients with acute coronary syndrome （ACS） after percutaneous coronary intervention （PCI） .Methods Fifty ACS pati ents after PCI were randomized into treatment group and control group with 25 in each.The control grou p was given the routine western medicine treatment

the treatment group was administered detoxificating and activating blood herbal medicine additionally.The levels of serum intercellular adhesive molecule-1 （ICAM-1） and P-selection were detected and the TCM s yndromes were scored to evaluate the effect.Results Af ter treatment

the seru m ICAM-1 and P-selection of the two groups were significantly lowered （P<0 .05）

and the comparison between the two groups was also statistically different （P <0.05）.The difference in the scores of TCM syndromes of the two groups before and after treatment was statistically significant （P<0.05）

and the difference in th e scores of TCM syndromes between the two groups after treatment was statistical ly significant （P<0.05）.The total effective rate was 92% and 72% in the tr eatme nt group and control group respectively with a statistical difference （P<0.05）.Conclusion The detoxificating and activating blood herbal medicine effe ctively decrease the ICAM-1 and P-selection expression of the ACS patients

indicatin g that it is able to inhibit the inflammatory reaction after PCI.