Objective To observe the clinical effect of acupoint injection with Chinese herbal medicine on oculomotor paralysis.Methods A total of 456 cases of oculomotor pa ralysis from three centers were randomized into treatment group and control grou p with 228 cases in each.In the treatment group

the main acupoints Jingming （BL 1）

Yangbai （GB 14）

Sibai （ST 2）

Tongziliao （GB 1） of affected side

and bilateral Ganshu （BL 18） were injected with Fufang Danggui Zhusheye （Injection of Compound Chinese An gelica）.The control group was treated routinely with western medicine.The treatment f or both groups lasted for 36 days

and the therapeutic effect was observed on th e scores of TCM syndrome

the eyeball movement degree of affected eye

and the c hanges in palpebral fissure and pupil.Results The tota l effective rate was 91 .7% and 73.7% in the treatment group and control group respectively with signi ficant difference （P<0.05）.The scores of TCM syndrome of both groups were signi ficantly reduced （P<0.05 or P<0.01）

and the reduction of the treatmen t group wa s more than that of the control group （P<0.05）.The eyeball movement degree of a ffected eye and palpebral fissure of both groups were improved （P<0.05 or P<0.01 ）

and the pupil was getting smaller （P<0.05）

the improvement of palpebral fiss ure and movement degree of musculus rectus medialis of eyeball of the treatment group was more than that of the control group （P<0.05）.Con clusion Acupoint in jection with Chinese herbal medicine Fufang Danggui Zhusheye is effective for oc ulomotor paralysis.