WANG Chenglong, ZHANG Dawu, WANG Peili, et al. Analysis on the TCM Syndrome Elements of Acute Coronary Syndrome[J]. Journal of Traditional Chinese Medicine2011, 52(19): 1654-1657.
WANG Chenglong, ZHANG Dawu, WANG Peili, et al. Analysis on the TCM Syndrome Elements of Acute Coronary Syndrome[J]. Journal of Traditional Chinese Medicine2011, 52(19): 1654-1657.DOI: 10.13288/j.11-2166/r.2011.19.011.
Objective To explore the distribution characteristics of TCM syndrome elements of acute coronary syndrome(ACS).Methods We collect 241 ACS cases confirmed by coronary contrast examination.They were scored with the global registry of acute coronary events(GRACE) according to their medical history
symptoms and signs
and the related laboratory tests.After the TCM syndrome elements were classified
those having influence on the prognosis of ACS and interacting on each other were screened out by using multi-factors dimension reduction(MDR) models and verified with the Logistic regression analysis.Results Of the 241 ACS cases
the most common syndrome was blood stasis
which manifested in 213 cases(88.4%).Those syndromes in the second place were qi deficiency
yin deficiency
phlegm turbidity with cold
phlegm turbidity with heat
yang deficiency
and qi stagnation.With the GRACE risk scoring
there were 21 cases(8.7%) of high-risk and 220 cases(91.3%) of medium-risk or low-risk.By using the MDR models and Logistic regression analysis
the Logistic regression equation was set up as logitP=-2.480+1.969(blood stasis + phlegm turbidity with cold + yang deficiency)
and the rate of risk of poor prognosis was 7.167(OR=7.167
95%CI:1.583
32.441).Conclusion The main syndrome elements of the ACS patients are blood stasis and qi deficiency
the occurrence of which is the highest in percentage.The accurence rate of all-cause death within 6 months is higher in those patients with the syndrome of yang deficiency + blood stasis + phlegm turbidity with cold than in those who were without the syndrome.