Objective To observe the therapeutic effect of Zhiyi Anquan Yin （Decoction for stopping enuresis） jointed with acupuncture on the infantile nocturnal enuresis （NE）. Methods Totally 108 NE children were randomized into Chinese herbal medicine group of 33 cases

acupuncture group of 34 cases

and Chinese herbal medicine plus acupuncture group of 41 cases. The Chinese herbal medicine group was administered decoction of Zhiyi Anquan Yin

100ml in the morning and in the evening respectively. The acupuncture group was treated with acupuncture at acupoints Guanyuan （CV 4）

Zhongji （CV 3）

Henggu （KI 11）

Guilai （ST 29）

Sanyinjiao （SP 6）

Shenshu （BL 23）

Yaoyan （EX-B7）

Shangliao （BL 31）

Ciliao （BL 32）

Zhongliao （BL 33）

Xialiao （BL 34）

Weizhong （BL 40）. The acupoints of front side and back side were alternatively used every other day

and the needles were retained for 20min each time. The Chinese herbal medicine plus acupuncture group was administered decoction of Zhiyi Anquan Yin and also treated with acupuncture. All three groups were treated for 20 days in succession. The frequency of NE of each week before and after treatment

during the 3-month follow-up

and the overall effect were observed. After the 3-month follow-up

the consolidation rate

gradually cured rate

and recurrence rate of the effective cases were followed up. Results In the Chinese herbal medicine group

19 cases （57.6%） were effective

in the acupuncture group

20 cases （58.8%） were effective

while in the Chinese herbal medicine plus acupuncture group

40 cases （97.6%） were effective. The total effective rate of Chinese herbal medicine plus acupuncture group was significantly higher than that of the other two groups （P<0.05）. The frequency of NE of the Chinese herbal medicine plus acupuncture group after treatment was significantly reduced （P<0.05）. After treatment and during the 3-month follow-up

the frequency of NE of the Chinese herbal medicine plus acupuncture group was also significantly lower than that of the other two groups （P<0.05）. The consolidation rate of the Chinese herbal medicine + acupuncture group after the 3-month follow-up was significantly higher and the recurrence rate significantly lower than those of the other two groups （P<0.05）. Conclusion Zhiyi Anquan Yin jointed with acupuncture is effective for children NE

and superior to the herbal medicine oral taking or acupuncture treatment only in result.