Objective To investigate the antithrombotic effect of Naoxintong Caps ule（Capsule for cerebro-coronary vascular diseases） on the patients undergoing percutaneous coronary intervention（PCI）.Methods Fifty-four coronary heart di sease patients

who had accepted revascularization by PCI successfully

were randomized into treatment group and control group

27 in each.Bot h groups were medicated with conventional postoperative antithrombotic treatment

while the treatment group was additionally administered Naoxintong Capsule

4 ca psules each time

3 times a day

for 1 month in succession.The scores of qi deficiency syndrome and blood stasis syndrome before treatment and 10 days after treatment

and on the short-term and long-term antithrombotic effect were observed

simultaneously

the safety of antithrombotic treatme nt of Naoxintong Capsule was evaluated.Results Compared w ith before treatment

in the treatment group the score of qi deficiency syndrome 10 d ays after treatment was significantly decreased（P<0.01）

while in the cont rol g roup it was significantly increased（P<0.01）.In both groups

the score of blood stasis syndrome

the maximum platelet aggregation（MPA） rate

the plasma heredi tary false hemophilia vonwillibrand factor（vWF）

the platelet membrane glycopro tein Ⅱ b/Ⅲ a（GP Ⅱ b/Ⅲ a）

the prothrombin segment 1 + 2 [F（1 + 2）]

and the fibrinogen（Fg） were reduced significantly 10 days after treatment（P< 0.01）

but the reduction in the treatment group was more significant（P<0.05）.In the duration of one-month follow-up after PCI

3 cases in the control group had a major adverse cardiovascular event（MACE）

none of the cases in the treatment group had MACE

a nd the difference between the two groups was not statistically significant in co mparison（P>0.05）.In the medication period

there were no major and second ary hemorrhagic complications in both groups.Conclusion In the patients with qi deficiency and blood stasis syndrome

combination of c onventional antithrombotic treatment and Naoxintong Capsule may decrease the sco res of qi deficiency syndrome and blood stasis syndrome 10 days after PCI

inhib it the activity of blood platelet

alleviate the damage of endothelial cells

an d improve the coagulation function.With the administration

there is a reducing tendency for the occurrence of cardiovascular events

and without the decrease of platelets and bleeding complications.