1. 新疆医科大学附属中医医院新药临床试验机构
2. 新疆医科大学
纸质出版:2012
移动端阅览
[1]王燕,袁海燕,周铭心.西北燥证与高血压病证关联性分析[J].中医杂志,2012,53(04):317-320.
WANG Yan1, YUAN Haiyan2, ZHOU Mingxin2. Analysis on the Correlation between the Northwest Dryness Syndrome and H ypertension[J]. Journal of Traditional Chinese Medicine2012, 53(4): 317-320.
[1]王燕,袁海燕,周铭心.西北燥证与高血压病证关联性分析[J].中医杂志,2012,53(04):317-320. DOI: 10.13288/j.11-2166/r.2012.04.007.
WANG Yan1, YUAN Haiyan2, ZHOU Mingxin2. Analysis on the Correlation between the Northwest Dryness Syndrome and H ypertension[J]. Journal of Traditional Chinese Medicine2012, 53(4): 317-320. DOI: 10.13288/j.11-2166/r.2012.04.007.
目的分析新疆维吾尔自治区高血压病与西北燥证的病证相关性
为从异病同治角度制定新疆维吾尔自治区高血压病防治策略提供流行病学依据。方法收集102例高血压患者为病例组
排除现代医学疾病而不排除亚健康罹患者173例为对照组
采取问卷量表形式对两组受试者进行中医证候评分、西北燥证评分
并对高血压病与西北燥证病证切合指数分析及高血压患者中医证候与西北燥证典型相关分析。结果病例组西北燥证罹患率31.37%
对照组为16.76%
病例组高于对照组(P<0.01)。病例组西北燥证总积分高于对照组(P<0.05);病例组肺卫孔窍皮肤燥证、心肾阴虚证及脾胃蕴湿证积分高于对照组(P<0.01)。高血压病情与西北燥证主兼证病证切合指数经检验差异均有统计学意义(P<0.05或P<0.01)。典型相关分析:第一典型变量r1=0.9072(P<0.01);高血压因变量组阴阳两虚证载荷量最大(0.5599)
自变量组脾胃蕴湿证载荷量最大(0.4191)。结论西北燥证是新疆维吾尔自治区大多数高血压患者的临床伴随证候
并以心肾阴虚证为突出表现
高血压各临床证候与西北燥证主兼证均有相关性
以阴阳两虚证与脾胃蕴湿证相关性最强。
Objective To analyze the correlation between the hype rtension in Xinj iang area and dryness syndrome in the northwest China in order to provide the ep idemiological basis for making the strategy for the prevention and treatment of hypertension from the treating different diseases with the same therapeutic prin ciple.Methods Totally 102 hypertension patients were attri buted to the case group
those 173 people who were without diseases but with the subhealthy state not e xcluded were put into the control group.The subjects of both groups were analyz ed with the questionnaire on the TCM syndrome score and northwest dryness syndro me score
the suit indices of hypertension with dryness syndrome
and typical co rrelation between the TCM syndromes of hypertension patients and northwest dryne ss syndrome.Results The incidence of northwest dryness syndrome in the case g roup was 31.37%
higher than 16.76% in the control group(P<0.01).The tota l sco re of northwest dryness syndrome in the case group was higher than that in the c ontrol group(P<0.05).The scores of the lung-defensive skin dryness syndr ome
y in deficiency of the heart and kidney syndrome
and damp retention of the spleen and stomach syndrome were higher than those in the control group(P<0.01).The suit indices of pathological conditions of hypertension with the main and accomp anied symptoms of northwest dryness syndrome after the test were all statistical ly significant(P<0.05 or P<0.01).The result of typical correlation analysis was as following:t he first typical variable r1 = 0.9072(P<0.01)
the load of the deficiency syndrome of both yin and yang of hypertension dependent variable group was the maximum(0.5599) an d the load of the damp retention of the spleen and stomach syndrome of the independe nt variable group was the maximum(0.4191).Conclusion The northwest dryness s yndrome is the accompanied syndrome of the most hypertension patients in the Xin jiang area
and it’s characterized by the typical manifestations of the yin deficiency of the heart and kidney syndrome.All clinical symptoms of hypertension a re correlated with both the main and accompanied symptoms of northwest dryness s yndrome
and the deficiency syndrome of both yin and yang and the syndrome of damp retention of the spleen and stomach were most strongly-correlated with hypertension.
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